Aromatase Inhibitors, Musculoskeletal Pain and Vitamin D

Keith Block, MD Arimidex (anastrozole), Aromasin (exemestane) and Femara (letrozole) are aromatase inhibitors (AIs) used to treat post-menopausal breast cancer patients whose cancer is estrogen receptor positive.  These medications block aromatase, an enzyme that converts androgens to estrogen, thus reducing the risk of cancer recurrence in this population.  However, aromatase inhibitors come with unwanted side … Continued

Common diabetes drug, metformin, appears to reduce cancer risk

Keith Block, MD  Metformin, a commonly prescribed drug for the treatment of type 2 diabetes, has been touted in several recent studies as having the potential to reduce the risk of cancer in people taking it to control their disease.   Metformin (Glucophage) helps control both insulin levels and the amount of glucose produced by the … Continued

When it comes to Chemotherapy, Timing’s Everything

Keith I. Block, MD When scheduling a health exam or procedure, most patients make their appointments based on convenience and availability. Research suggests there’s something else they should take into account: Timing.  Timing, as in the administration of any drugs they may be given, and timing, as in their own “biological clocks.”   We now know … Continued

Preventing Colon Cancer: What You Need to Know

By Keith Block, MD According to the Colon Cancer Alliance, colorectal cancer is the third most commonly diagnosed cancer in the United States, and the second leading cause of cancer deaths.  The American Cancer Society estimates that in 2012, 143,460 people will be diagnosed and that 51,690 will die from colon cancer in the United … Continued

Getting the Most Out of Tamoxifen

By Keith Block, MD Many women with breast cancer are aware of a recent long-term British study showing that taking the generic drug tamoxifen for five years resulted in a significantly lower risk of their cancer returning when compared to only taking the drug for two years.  In this clinical trial, nearly 3,500 breast cancer … Continued

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